Longevity Blogs

Discover insightful articles on health, wellness, and the habits that support a longer, stronger life.

Showing 1 to 7 of 7 articles

Staged‑Evidence Pathways: How Bayesian Tools and Conditional Approvals Are Creating New Translational Templates for Geroscience

Why the idea of a “staged” evidence pathway matters now Over the past 18 months regulators and sponsors have produced a set of operational precedents that, take...

May 8, 2026
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FDA’s Bayesian and RWE Push: Practical next steps for geroscience trials

Regulatory momentum: two complementary shifts In the first four months of 2026 the FDA published a draft guidance that explicitly endorses practical use of Baye...

May 6, 2026
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How 2025–2026 Funding and a Canine Drug Pathway Are Rewiring Geroscience Translation

Summary In the last 12–18 months U.S. geroscience has moved from isolated pilot projects toward a coordinated translational stack: new center grants and cores,...

May 6, 2026
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Mixed Signals from Early Human Rapamycin Trials: What the 2025–2026 Data Actually Show

Where the human data stand Over the past two years a small but growing set of randomized and pilot human trials has begun to test whether rapamycin or related "...

May 6, 2026
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Tissue-Targeted Senolytics Meet Better Biomarkers: A Practical Roadmap for Near-Term Geroscience Trials

Why tissue delivery and better biomarkers matter now Over the past 18 months a distinct translational pathway for geroscience has gained momentum: local deliver...

May 4, 2026
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Why the FDA’s LDT Reversal Is Rewiring Biomarker and Endpoint Strategy in Longevity Trials

Summary The U.S. federal court decision and subsequent FDA action that vacated the 2024 LDT final rule has immediate, practical consequences for how longevity a...

May 4, 2026
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First human test of partial epigenetic reprogramming marks a cautious turning point for geroscience trials

Life Biosciences’ ER-100 IND clearance: what happened On Jan. 28, 2026, Life Biosciences announced that the U.S. Food and Drug Administration had cleared an inv...

May 4, 2026
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